Retinol targeting complex to be introduced in Artistry firming serum Retinol targeting complex to be introduced in Artistry firming serum 26-May-2011 By Pooja Kondhia US-based skincare line Artistry from Amway, has utilized a patented targeting complex technology from the University of Michigan into its anti-wrinkle serum, which it claims reduces common side effects associated with retinol treatments.